![]() ![]() Vitiligo universalis skin#Since total repigmentation may not occur even after receiving 150 sessions of PUVA therapy alone, these patients are naturally more interested in depigmentation therapy to achieve uniform skin tone. DIHS patients have been reported to subsequently develop autoimmune disease. Depigmentation Therapy for People with Universal VitiligoĪt times, people with universal vitiligo have one or more pigmented patches that remain pigmented, most frequently over the malar area of the face and dorsal areas of forearms. Druginduced hypersensitivity syndrome (DIHS) is a type of severe drug adverse reaction with high morbidity and mortality. Statistically, noteworthy differences were also seen in physical HRQOL between two groups of patients with a poorer outcome in patients with universal vitiligo. Additionally, Alopecia areata was reported in 4 patients with universal vitiligo, but none of the patients with general vitiligo had Alopecia areata. The most frequently comorbidities mentioned in the studies were Thyroid Dysfunction, Diabetes Mellitus, Rheumatoid Arthritis and Alopecia areata.Īs per this study, people with universal vitiligo seem to experience 15% Rheumatoid Arthritis (RA) compared to patients with general vitiligo that experience 3% RA. However, as per a study (with the sample size of 29) conducted by the Netherlands Institute for Pigment Disorders (NIPD), patients with vitiligo of universal nature reported considerably more comorbidities (the presence of one or more additional conditions) than the patients with general vitiligo. So far, studies about health-related quality of life (HRQOL) in patients with universal vitiligo have been conducted with a limited sample size. Quality of Life in People with Universal Vitiligo Permanent de-pigmentation with timedsurgical mixed peeling of normal facial skin in vitiligo universalis KEYWORDS: Vitilig. While it’s a little easier for people with this kind of vitiligo to deal with the condition compared to those living with aggressive nonsegmental vitiligo, it’s a bit of a struggle having to deal with the racial dynamics of turning white. This is represented by a high prevalence of comorbidity. Since this kind of vitiligo represents the high end of the spectrum in general vitiligo. Universal vitiligo ultimately leads to complete depigmentation of the skin, mucosa, and hair. It is characterized by the wide distribution of the vitiligo patches throughout the body with only isolated islands of normal pigmentation remaining. Universal vitiligo is an uncommon type of vitiligo in which more than 80% of the skin is covered in white, milky lesions. ![]()
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